8th Willem Wijnberg Cancer Fundraiser 2011
through to July 11th 2011
The 2011 Willem Wijnberg Cancer Fundraiser
has been a record setting fundraiser this year. Prior to this year,
the highest amount we had raised with our fundraisers was the 2005
Willem Wijnberg Fundraiser, where we raised $31,185.63. This year we
were trying to raise $35,000 to support Dr. Matthew Breens
Histio Research Study. We smashed right past our goal and didnt
stop there! As of today, we have raised a total of $45,524.71. When
you add the additional $10,000 from the George Pappas/Fara Bushnell
and the Anonymous Donors, that brings the total to $55,524.71!!!
CONGRATULATIONS TO EVERYONE FOR A TOTALLY AWESOME FUNDRAISING
We will be able to fully fund the Berner
research study on histio for Dr. Breen, and we will have an
additional $20,000 plus to continue that research once it is done.
We usually average around 159 donors for our fundraisers but for
this fundraiser we had 468 donors. We had 100% participation from
the regional clubs in the USA and donations from the BMDCA and the
BMD Club of Canada. Two regional clubs in Canada and the BMD Club of
Great Britain also made donations. We had donations from 43 of the
50 states in the USA, from 5 of the 13 provinces and territories in
Canada, and from 4 other countries.
Here is the list of donations by states,
provinces/territories and countries:
AK - 7, AL - 2, AZ - 11, CA - 50, CO - 28,
CT - 7, DC - 1, FL - 4, GA - 12, IA - 2, ID - 4, IL - 15, IN - 10,
KS - 4, KY - 5, LA - 1, MA - 26, MD - 15, ME - 5, MI - 10, MN - 5,
MO - 6, MT - 2, NC - 15, NE - 2, NH - 6, NJ - 5, NM - 2, NV - 6, NY
- 25, OH - 22, OR - 13, PA - 24, RI - 3, SC - 3, TN - 8, TX - 10, UT
- 2, VA - 16, VT - 5, WA - 16, WI - 5, WY - 1, USA - 1, Alberta - 6,
Australia - 9, Ontario - 16, British Columbia - 6, Yukon - 1, Italy
- 1, Mexico - 1, Netherlands - 1, UK - 5.
Way out ahead in first place is California
with 50 donations! Second place is Colorado with 28 donations, third
place is Massachusetts with 26 donations, and fourth place is New
York with 25 donations!!
THANK YOU ALL FOR YOUR FANTABULOUS SUPPORT
- What power we have when we put our minds to accomplishing
THANK YOU WILLEM WIJNBERG for once again
painting all of the items for our A prizes! Your dedication and
talent is something very special, as are you!
THANK YOU TO DR. MATTHEW BREEN for not only
doing histio and other cancer research, but also for donating a "Day
in the Breen Lab" as a prize for our fundraiser. There were a
huge amount of tickets in the envelope for his prize! (I will also
post a thank you letter from Dr. Breen that I received today.)
THANK YOU JEAN CHEESMAN for once again
making the wonderful website so people can view the prizes and see
how to make donations. I know that I kept you very busy with all of
our challenges this year, but we certainly got great results!!
THANK YOU GEORGE PAPPAS, FARA BUSHNELL, AND
ANONYMOUS for making challengs that brought in a tremendous amount
of donations - You gave us something to strive for and Berner Lovers
came through like the champions they are.
THANK YOU to the Berner Lovers who donated
prizes so we could have a "B" tier of prizes this year and
who made donations to fight histio in Berners.
THANK YOU to the people who donated their
tickets to use as a challenge to encourage more donations from
THANK YOU TO TOOK VISUDTIBHAN for donating
the pottery to Willem for the prizes. --
Joye Neff and Maine's Xephyr Alpinebear,
CGC - "Breeze" - BG #72657
and "Will" (German Shorthair
Breeze helps Joye pick the Winner for a "Day
in the Breen Lab"
FOR A TON OF TICKETS>
Note I received today, July 19th, from Dr.
Matthew Breen about our fundraiser and his research.
In a previous study (funded by CHF-760) we
demonstrated that canine histiocytic malignancies (HMs) in Berners
present with a high degree of DNA copy number alteration. We
identified several aberrant regions of the genome that are highly
recurrent between cases, suggesting that such regions are associated
causally with the malignant process. Understanding the biology of
genes within such regions is key to developing ways to halt the
cancer and prolong life in patients whom otherwise have a poor
prognosis. We now have an approach to identify DNA copy number
changes that allows us to zoom in on regions of the genome with
~75-fold greater resolution than was possible even just one year
ago. Using this technology we will refine the genome regions of
interest defined in CHF-760 and identify additional, smaller
aberrations. Within these regions we aim to identify a series of
candidate genes for functional analysis. We have developed an assay
for use with archival canine tumor samples that allows us to rapidly
determine the level of activity of multiple genes with higher
sensitivity than was possible previously. Once we have identified
the key genes of interest, we will use this assay to screen HM cases
for the extent of gene deregulation. In this study we will also
identify DNA copy number changes that are shared with human HMs.
Combining these approaches, we will narrow down the search for genes
playing a key role in HMs and thus move a step closer to developing
targeted therapies for canine patients diagnosed with this
devastating cancer. This new study forms the basis of a pending
grant submitted to AKC-CHF, who will make a funding decision in
I would like to express my sincere thanks
to everyone who contributed to the 2011 Willem Wijnberg Cancer
Fundraiser. I am thrilled that the proceeds will be made available
to support our ongoing work with Berners. In recognizing that the
Berner community is fully behind this work, I hope that the AKC
Canine Health Foundation will provide the additional funding needed
to perform this project to the extent we have proposed. However,
with the funds generously donated to this cause, I can confirm that
we will be able to complete the Berner component of this larger
project. From a personal perspective, it is fantastic to see so much
money raised for the research, especially in these financially
challenging times. By soaring past the original goal, you have
collectively sent out a very strong message of hope and confidence
in what we are doing. I would like to assure you (and the Berners)
that we will do all we can to live up to your expectations. Once the
initial aims have been completed, the additional funds would allows
us to immediately begin the next step of this work, which would
involve identifying druggable targets that may be considered for
development of new therapies for MH.
Matthew Breen ~
Home Page Collection 2010
Compiled by Pat Long and Jaime Meyers
Benefiting Berner Cancer Research
2011 K9 Cancer Walk, Elk Grove, Calif.
May 7th 2011
support of Morris Animal Foundation's Canine Cancer Campaign .
here is a very special picture,
Willem at work on Amika's painting
for our Angel Pin Lady, Karen Connors,
We love you!!!!!
For the Histio Roll
Call of just some of our Berners lost to this cancer
and why your
donations are so very important!
information on all aspects of canine cancer care
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